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So, the new info I decided to Google after studying GABA and reading the review on Stratter: >> The results of our meta-analysis show that magnesium levels in peripheral blood, plasma, serum, or whole blood, were significantly lower in children diagnosed with ADHD than in the control group. https:/ /sci-hub.et-fine.com/10.1016/j.pnpbp. 2018.11.012 Magnesium (Mg2+) is the second most abundant cation in the human intracellular compartment and is of great physiological importance [24]. It plays an important role in more than 300 metabolic reactions involved in protein synthesis, nucleic acid production and cellular energy production [25]. Thus, low magnesium levels are associated with a number of chronic diseases. The role of magnesium in nerve tissue is discussed [26]. Magnesium’s involvement in the pathogenesis of ADHD may be due to its role in nerve cell apoptosis by controlling the glutamate-N-methyl-aspartate pathway [27] and its crucial role in converting essential fatty acids into polyunsaturated fatty acids omega-6 and omega-3 acids, which are important cofactors of desaturase enzymes involved in hyperactive behavior [28]. >> Magnesium deficiency is associated with impaired cognitive abilities, leading to symptoms such as fatigue, lack of concentration, nervousness, mood swings and aggression [29]. Since these symptoms are characteristic of ADHD, it is not surprising that most studies show lower serum magnesium levels in patients with ADHD compared to healthy people [30,31,32,33,34,35,36,37]. However, in a minority of clinical studies, patients with ADHD had serum magnesium levels similar to [38.39] or even higher than their healthy peers [28.40]. However, two recent reviews and meta-analyses of serum magnesium levels concluded that children with ADHD had lower levels than children without ADHD [41,42]. Four studies found lower levels of magnesium in red blood cells [38,43,44,45] or lower activity of Mg2+-ATphase [45]. Intracellular magnesium may be the best indicator of Mg status. Increased blood concentration, on the other hand, may be associated with therapeutic administration of stimulant drugs, as has been shown [46]. Mg levels in saliva were significantly reduced in patients with ADHD [47], as well as in hair [42,48]. Only one older publication on magnesium in the urine was found that reported lower levels in individuals with ADHD compared to healthy individuals [30]. https://www.ncbi.nlm.nih.gov/pmc/articles/ PMC7583976/