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Technically the Chinese themselves are also to blame, as they caused the Boxer Rebellion and thus the Wuchang Uprising by jointly massacring Prussian/Japanese/British diplomats, and then overthrowing their own government for being invaded by them. Then the said Japanese invaded again, which left the power vacuum to later establish the PRC.
I wouldn't really blame them, as China always hated foreign merchants, spies, and diplomats and so do I, but don't blame it solely on the USA. They weren't even involved in the Boxer and Wuchang rebellions.