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> It looks like in Guilty Gear some of the chars use musical instruments? How?

By smashing it on the opponent's head I believe. And some kind of magic idk. I think it's just one character, I-No. The rest of the cast uses some kind of weapons, or hands. Or a giant anchor. The tone of the game is quite wacky so I try to not overthink it. 
https://youtube.com/watch?v=M9iudq6s8Us