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There were other successful negotiations - eg. Libya and Sudan - but there were bunch of failed ones, that went on and off, they opened talks but things got derailed over and over: Cuba, Syria, Iran, North Korea. When failure occur it seems the blame is always on both sides, but it seems to me from the American side, they usually don't see the strategic advantage to see through the change. For example in case of China the whole process was supported by three consequent presidents, it was just too important. So if there is no immediate threat, then it will depend a lot on how the various power blocks within the US see the enemy and the benefits.

picrel: Muammar Gaddafi, how I see it they negotiated his weapons away, the US and Western Europe made him give up aspirations for nukes, and his chemical weapons, and then they killed him off with the Arab Spring. I bet Iran learnt a lot from this lesson.