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Well the South front is much more important, if they capture Zaporizhya they can basically destroy UA logistics.
Donbass is politically important (it is RU number one goal) plus it is the main stronghold of the East.
It happened many times during this war. UA army moves its troops -> makes some tactical advances -> and meanwhile loses other strategically important areas.

> Plus. The original separatist regions beyond Dontesk and Lugansk were Odessa, Dnipro, and Kharkov in 2014.
Yes, but (as for now) Russia didnt even include it in its constitution. Actually they are ready to withdraw troops from Kharkov region in exchange for Donbass.
And btw Odessa is even more important not only because it is a huge port city, but because it is historic Russian imperial city, built by Russian Empire and basically a symbol or Russian exploration of the South.