This is a "popular" many-file simple folder from ~years ago:
ipfs://QmVfF4zAq5jMQT75cpao5ZM53LKhocM17N4QjP8PvAFQFY
. where? In HTTP, IPFS, and multiple HDDs of mine (none of which are turned on right now)
. what? Roughly 1.9 gigabytes of MLP-related pastebin.com pastes: possibly "minimally" modified (such as DOS->UNIX newlines) for https://poneb.in - includes clopfics and stuff
. status? Significantly ipfs-offline right now

 >>/10588/
> a My Little Karaoke ISO
More learning with that... Contents:
> $ ipfs ls /ipfs/QmYKQHEYePN4Yf9g6a2hNA54APyNu8Bd4tVwKMWSBhkn6g
> QmUxhgpxusP5Rm1TGq2SnS7bnMiVmCENPyt96CiT5qFmjt 3180709888 MLK_AC2.iso
> $ ipfs ls /ipfs/QmUxhgpxusP5Rm1TGq2SnS7bnMiVmCENPyt96CiT5qFmjt | head -n3
> QmdgL78gZHxNv1aRbdxvkj3VGKuTyGoWMdmr38VfYX21zZ 182452224 
> QmW5BXwzzPVjgCRgfDZUAQvRGzebeqEGyu3mtHSSLCSykB 182452224 
> QmfKy9GpWs8TiHdeRvN7cRbf3QomZdZbEtQmzafwgqT1hW 182452224 
> $ # last block = QmfVt2WUJC8FTVapmvt5SKmVz6zwfrKZY4hLbJ8oPDDeZE 79022080  
Can't open a multi-gigabyte file as a folder and view IPLD blocks:
> [pcmanfm:] The specified directory '/ipfs/QmUxhgpxusP5Rm1TGq2SnS7bnMiVmCENPyt96CiT5qFmjt' is not valid
Can mount the first n megabytes of an ISO file, but "all of" the audio files in there didn't play with "mpv --no-video z":
> $ gnome-disk-image-mounter /ipfs/QmdgL78gZHxNv1aRbdxvkj3VGKuTyGoWMdmr38VfYX21zZ
> $ sudo mount /dev/loop0 /mnt/z
> mount: /mnt/z: WARNING: source write-protected, mounted read-only.
> $ # Didn't work due to spanning data/files maybe, kinda like cluster runs in NTFS?
So with ISO files, if the index data is far away from the payload data, then I could see how that could be a problem.