https://www.equestriadaily.com/2020/04/tara-strong-notes-that-twilight-sparkle.html

well, you were asking for more information about Pony Life, gen 5 or the comics...

It seems that we have something to latch ourselves for a bit when it comes to that discussion. Maybe not now because you have more posts to reply yet but I am leaving the EQD in which they confirm that Tara Strong isn´t currently voicing for Twilight Sparkle. This implies two possible routes here: either the mane 6 reappear again but with a different group of VA (at least, Twilight) or Tara voices another character that is not Twilight for gen 5. 

With that said, gen 5 production is paralyzed because of the current circumstances but at least, this could imply a wind of change for the next generation but it´s really unclear.