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Actually now that I think of it, porn and internet addiction cause lasting (but reversible) changes to the brain, especially the reward centers (desensitisation, hypofrontality, sensitisation, stress-response changes, etc.) leading to an increasing change in tastes seeking novelty
https://www.scribd.com/document/348230501/FTND-Harmful-Effects-of-Pornography-s-10915-pdf
https://www.yourbrainonporn.com/research-articles-and-abstracts
I haven't looked very far into the hormonal effects, but there's obviously some relationship between jerking off to BBC POV or hentai all day and hormone profiles